This paper argues the need to expand the research agenda on the use of ICT in African countries to include a stronger strategic developmental focus than is evident in much of the literature to date. Four strategic dimensions are identified, where ICT arguably has potential as a significant enabler for transformational development in Africa: institutional infrastructure; governance, accountability, and civil society; service production and economic activity; and access to global markets and resources. A representative set of literature on IS in Africa is classified along these dimensions, but an explicit focus on development is found to be lacking in most of this work. The four dimensions are then discussed in turn to describe their importance in the African context, to discuss some pathfinding research examples to date and to identify some directions for future research. The paper concludes with a call for IS researchers working on Africa to become involved in debate on national and international policy from an ICT perspective and to engage with other research communities in doing this, notably with those concerned with the field of African development.